Corteva, Alveo Technologies Form Collaboration to Advance Molecular Crop Disease Diagnostics

Alveo Technologies, Inc. has announced a collaboration with Corteva Agriscience to expand the offering of its novel eco-friendly molecular sensing and disease diagnostics technology to include a first-in-field agricultural disease diagnostic.

Alveo has developed a rapid, handheld, portable medical-grade platform that pairs advanced molecular assays with cloud-enabled data analytics for real-time disease, pathogen analysis, and diagnosis. Using this highly sensitive multiplexed molecular testing platform, Corteva scientists aim to design crop-specific assays to detect pathogens in the field.

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“Alveo has developed a game changing, mobile ‘molecular lab’ that can deliver highly sensitive and specific diagnostic testing where it is needed, which can help solve some of the world’s most complex problems, like pandemics and global food crises,” said Alveo CEO Shaun Holt. “Our collaboration with Corteva reflects our core focus of taking molecular testing out of the lab and directly to the point of need where it can deliver insight and guidance. This partnership extends the technology beyond healthcare and into agricultural applications.”

“Corteva Agriscience explores the latest technologies as we strive to bring actionable insights and solutions to farmers where and when they need them,” said Gina Zastrow-Hayes, Technical Director, Seed, R&D & Biotechnology, Corteva. “We are pleased to explore this feasibility with Alveo and are excited by the potential that in-field molecular testing platforms hold for the agricultural industry.”

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Alveo’s be.well platform is a point-of-care infectious disease diagnostic platform that utilizes the company’s proprietary and globally patented method for the direct electrical sensing of nucleic acid amplification. This technology eliminates the need for specialized lighting and expensive optical detectors, while also simplifying certain aspects of primer manufacturing, providing a more robust and reliable diagnostic instrument.

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Corteva scientists will explore three components of the platform to develop agri-based assays: the be.well Analyzer, a portable, palm-sized, rechargeable device; the be.well Cartridge which contains the reagents required for an isothermal amplification reaction; and the be.well Mobile App which offers step by step guidance on administering the test, cloud-connectivity for reporting and tracking results, and back-end analytics for deeper insights into pathogen behavior.

This collaboration reflects both companies’ open-source philosophy and desire to build together across sectors and technologies.

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